15 deoxy Delta 12,14 Prostaglandin J2 antibody,Genetex,GTX22313

Host

Rabbit

Reactivity

Species independent

Application

ELISA RIA

Conjugate

Unconjugated

Platform ID

BAB237942728

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Name15 deoxy Delta 12,14 Prostaglandin J2 antibody
Cat. No.GTX22313
HostRabbit
IsotypeIgG
ReactivitySpecies independent
ConjugationUnconjugated
ApplicationELISA RIA
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
Immunogen15-deoxy-D12,14-Prostaglandin J2 conjugated to a protein carrier molecule
Appearance/FormLiquid
FormulationPBS,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

15-deoxy-Delta12,14-Prostaglandin J2 (15-d-PGJ2) is one of the ultimate dehydration products of PGD2, formed via the intermediate Delta12-PGJ2. 15-d-PGJ2 is physiologically present in body fluids at concentration of 10-12 to 10-9 M, but increases dramatically under stress such as infection and inflammation. 15-d-PGJ2 exerts both pro- and anti-inflammatory effects in a cell-type and concentration-dependent manner, with many of these effects mediated via binding to the gamma isoform of the peroxisome proliferators-activated receptor (PPAR-gamma). 15-d-PGJ2 appears to induce HO-1 expression by a PPAR-gamma-independent mechanism mediated by the generation of reactive oxygen species (ROS).

Synonyms

Prostaglandin J2

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.