α2-Adrenergic Receptor Antibody Explorer Kit,Alomone Labs,AK-495_KIT

Adrenergic receptors (also called adrenoceptors) are the receptors for the catecholamines; adrenaline and noradrenaline (called epinephrine and norepinephrine in the United States). Adrenaline and noradrenaline play important roles in the control of blood pressure, myocardial contractile rate and force, airway reactivity, and a variety of metabolic and central nervous system functions. Adrenoceptors are members of the G-protein coupled receptor (GPCR) superfamily of membrane proteins. They share a common structure of seven putative transmembrane domains, an extracellular N-terminus, and a cytoplasmic C- terminus. The adrenoceptors are divided into three types: α 1 , α 2 and β-adrenoceptors. Each type is further divided into at least three subtypes: α 1A , α 1B , α 1D , α 2A , α 2B , α 2C , β 1 , β 2 , β 3 1,2 . The adrenoceptors are expressed in nearly all peripheral tissues and in the central nervous system 1,2 .