4-Hydroxynonenal Rabbit mAb- ABclonal,ABclonal,A26085
Reactivity
Species independent
Application
WB, IF/ICC, IF-P, FC (intra)
Conjugate
Unconjugated
Platform ID
BAB346345612
ABclonal
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Product Specifications
Scientific Background
Synonyms
Specifications
Name4-Hydroxynonenal Rabbit mAb- ABclonal
Cat. No.A26085
RRIDRRID: AB_3718713
IsotypeIgG
ReactivitySpecies independent
ConjugationUnconjugated
ApplicationWB, IF/ICC, IF-P, FC (intra)
Working DilutionsWB:1:1000 - 1:10000 | IF/ICC:1:200 - 1:500 | IF-P:1:200 - 1:500 | FC (intra):1:100 - 1:500
Clone NumberARC70314
Molecular Weight42-350kDa
ImmunogenChemical compounds corresponding to 4-Hydroxynonenal.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only
Scientific Background
4-hydroxy-2-nonenal (4-hydroxynonenal, 4-HNE) is a highly reactive aldehyde generated by the exposure of polyunsaturated fatty acids to peroxides and reactive oxygen species (ROS). It non-enzymatically forms stable protein adducts with histidine, lysine, and cysteine side chains that have been used as biomarkers for oxidative damage in cells. Conditions where 4-HNE immunoreactivity has been observed include include inflammation, neurodegenerative diseases, and ischemic damage to the heart and brain.
Synonyms
4-HNE
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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