5-HT2A receptor antibody,Genetex,GTX37799

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB IHC-P IHC-Fr FCM

Conjugate

Unconjugated

Platform ID

BAB584632559

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

Name5-HT2A receptor antibody
Cat. No.GTX37799
Gene ID (Entrez)3356
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB IHC-P IHC-Fr FCM
ClonalityPolyclonal
Concentration0.5 mg/ml (Please refer to the vial label for the specific concentration.)
TargetHTR2A
ImmunogenKLH conjugated synthetic peptide derived from human 5HT2A Receptor (65-160/471AA).
PurityProtein A purified
Appearance/FormLiquid
Formulation10mM TBS, 0.5% BSA, 25% Glycerol,0.015% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Synonyms

5-hydroxytryptamine receptor 2A , 5-HT2A , HTR2

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