ABflo® 450 Rabbit anti-Human/Monkey CD127/IL-7Rα mAb,ABclonal,A26070

Reactivity

Human, Cynomolgus

Application

FC

Conjugate

ABflo® 450. Ex:406nm. Em:445nm.

Platform ID

BAB490087847

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NameABflo® 450 Rabbit anti-Human/Monkey CD127/IL-7Rα mAb
Cat. No.A26070
RRID#N/A
IsotypeIgG
ReactivityHuman, Cynomolgus
ConjugationABflo® 450. Ex:406nm. Em:445nm.
ApplicationFC
Working DilutionsFC:5 μl per 10^6 cells in 100 μl volume
Clone NumberARC66004
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at 2-8℃. Avoid freeze.; Buffer: PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.

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