ABflo® 450 Rat anti-Mouse CD314/NKG2D mAb,ABclonal,A28364

Reactivity

Mouse

Application

FC

Conjugate

ABflo® 450. Ex:406nm. Em:445nm.

Platform ID

BAB188376416

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

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Product Specifications
Scientific Background

Specifications

NameABflo® 450 Rat anti-Mouse CD314/NKG2D mAb
Cat. No.A28364
RRID#N/A
IsotypeRat IgG1
ReactivityMouse
ConjugationABflo® 450. Ex:406nm. Em:445nm.
ApplicationFC
Working DilutionsFC:≤0.25 µg per million cells in 100 µl volume
ImmunogenThis information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at 4℃. Avoid freeze.; Buffer: PBS with 0.09% Sodium azide and BSA, pH7.2.
Regulatory StatusResearch Use Only

Scientific Background

Enables several functions, including MHC class I protein binding activity; MHC class Ib receptor activity; and identical protein binding activity. Involved in positive regulation of natural killer cell mediated cytotoxicity. Acts upstream of or within several processes, including positive regulation of biosynthetic process; response to bacterium; and stimulatory C-type lectin receptor signaling pathway. Located in external side of plasma membrane. Human ortholog(s) of this gene implicated in HTLV-1-associated myelopathy/tropical spastic paraparesis. Orthologous to several human genes including KLRK1 (killer cell lectin like receptor K1).

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