ABflo® 488 Rabbit anti-Human CD123 mAb,ABclonal,A28500

Reactivity

Human

Application

FC

Conjugate

ABflo® 488. Ex:491nm. Em:516nm.

Platform ID

BAB751607315

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NameABflo® 488 Rabbit anti-Human CD123 mAb
Cat. No.A28500
RRID#N/A
IsotypeIgG
ReactivityHuman
ConjugationABflo® 488. Ex:491nm. Em:516nm.
ApplicationFC
Working DilutionsFC:5 μl per 10^6 cells in 100 μl volume
Clone NumberARC79001
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at 2-8℃. Avoid freeze.; Buffer: PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

CD123 is the 70 kDa transmembrane alpha chain of the interleukin-3 (IL-3) receptor. It binds IL-3 with low affinity when alone; however, upon association with CD131 (the common beta chain), the complex binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon IL-3 binding and requires the beta chain for this function. CD123 is expressed on bone marrow precursor cells, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and certain B-cell populations.

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