ABflo® 488 Rabbit anti-Human CDA mAb,ABclonal,A24685

Reactivity

Human

Application

FC (intra)

Conjugate

ABflo® 488. Ex:491nm. Em:516nm.

Platform ID

BAB181679632

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NameABflo® 488 Rabbit anti-Human CDA mAb
Cat. No.A24685
RRID#N/A
IsotypeIgG
ReactivityHuman
ConjugationABflo® 488. Ex:491nm. Em:516nm.
ApplicationFC (intra)
Working DilutionsFC (intra):5 μl per 10^6 cells in 100 μl volume
Clone NumberARC63546
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at 2-8℃. Avoid freeze.; Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.

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