ABflo® 488 Rabbit anti-Human CaSR mAb,ABclonal,A26713
Reactivity
Human
Application
FC
Conjugate
ABflo® 488. Ex:491nm. Em:516nm.
Platform ID
BAB123496309
ABclonal
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Product Specifications
Scientific Background
Specifications
NameABflo® 488 Rabbit anti-Human CaSR mAb
Cat. No.A26713
RRID#N/A
IsotypeIgG
ReactivityHuman
ConjugationABflo® 488. Ex:491nm. Em:516nm.
ApplicationFC
Working DilutionsFC:5 μl per 10^6 cells in 100 μl volume
Clone NumberARC69622
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at 2-8℃. Avoid freeze.; Buffer: PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3.
Regulatory StatusResearch Use Only
Scientific Background
The protein encoded by this gene is a plasma membrane G protein-coupled receptor that senses small changes in circulating calcium concentration. The encoded protein couples this information to intracellular signaling pathways that modify parathyroid hormone secretion or renal cation handling, and thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene are a cause of familial hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism, and autosomal dominant hypocalcemia.
Category Paths
- Products>Primary Antibodies>Conjugated Antibodies
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