ABflo® 488 Rabbit anti-Human EGFR mAb,ABclonal,A24265

Reactivity

Human

Application

IF/ICC, FC

Conjugate

ABflo® 488. Ex:491nm. Em:516nm.

Platform ID

BAB424508076

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NameABflo® 488 Rabbit anti-Human EGFR mAb
Cat. No.A24265
RRID#N/A
IsotypeIgG
ReactivityHuman
ConjugationABflo® 488. Ex:491nm. Em:516nm.
ApplicationIF/ICC, FC
Working DilutionsIF/ICC:1:50 - 1:200 | FC:5 μl per 10^6 cells in 100 μl volume
Clone NumberARC61443
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at 2-8℃. Avoid freeze.; Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

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