ABflo® 488 Rabbit anti-Mouse CD127/IL-7Rα mAb,ABclonal,A24788

Reactivity

Mouse

Application

FC

Conjugate

ABflo® 488. Ex:491nm. Em:516nm.

Platform ID

BAB307141910

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NameABflo® 488 Rabbit anti-Mouse CD127/IL-7Rα mAb
Cat. No.A24788
RRID#N/A
IsotypeIgG
ReactivityMouse
ConjugationABflo® 488. Ex:491nm. Em:516nm.
ApplicationFC
Working DilutionsFC:5 μl per 10^6 cells in 100 μl volume
Clone NumberARC63550
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at 2-8℃. Avoid freeze.; Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

Interleukin-7 is a glycoptorein involved in the regulation of lymphopoiesis. Response of cells to IL7 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is a alpha/gamma chain heterodimer. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules.

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