ABflo® 488 Rabbit anti-Mouse CD324/E-Cadherin mAb,ABclonal,A26483

Reactivity

Mouse

Application

FC

Conjugate

ABflo® 488. Ex:491nm. Em:516nm.

Platform ID

BAB052119322

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NameABflo® 488 Rabbit anti-Mouse CD324/E-Cadherin mAb
Cat. No.A26483
RRID#N/A
IsotypeIgG
ReactivityMouse
ConjugationABflo® 488. Ex:491nm. Em:516nm.
ApplicationFC
Working DilutionsFC:5 μl per 10^6 cells in 100 μl volume
Clone NumberARC68219
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at 2-8℃. Avoid freeze.; Buffer: PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes E-cadherin, a calcium-dependent cell adhesion molecule that functions in the establishment and maintenance of epithelial cell morphology during embryongenesis and adulthood. The encoded preproprotein undergoes proteolytic processing to generate a mature protein. Targeted mutations disrupting binding of calcium to the encoded protein in mice cause death in utero due to failed blastocyst and trophectoderm formation. This gene is located adjacent to a related cadherin gene on chromosome 8.

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