ABflo® 488 Rabbit anti-Mouse CD49a/ITGA1 mAb,ABclonal,A26654

Reactivity

Mouse

Application

FC

Conjugate

ABflo® 488. Ex:491nm. Em:516nm.

Platform ID

BAB998733695

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameABflo® 488 Rabbit anti-Mouse CD49a/ITGA1 mAb
Cat. No.A26654
RRID#N/A
IsotypeIgG
ReactivityMouse
ConjugationABflo® 488. Ex:491nm. Em:516nm.
ApplicationFC
Working DilutionsFC:5 μl per 10^6 cells in 100 μl volume
Clone NumberARC68868
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at 2-8℃. Avoid freeze.; Buffer: PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

CD49a is a 1179 aa, type I transmembrane glycoprotein also known as α1 integrin, VLA-1 α chain, or integrin α1. It associates antibody v042010 with CD29 (β1 integrin) to form the VLA-1 complex, a collagen IV and alminin-1 receptor that is expressed on activated T cells, smooth muscle cells, endothelial cells, neuronal cells, fibroblasts, and mesenchymal cells. CD49a is an adhesion molecule and is involved in the regulation of leukocyte migration, T cell proliferation, and cytokine production.

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