ABflo® 500 anti-Mouse PD-1/CD279 mAb,ABclonal,A28365

Reactivity

Mouse

Application

FC

Conjugate

ABflo® 500. Ex:410nm. Em:501nm.

Platform ID

BAB500882663

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Fax:

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameABflo® 500 anti-Mouse PD-1/CD279 mAb
Cat. No.A28365
RRID#N/A
IsotypeArmenian Hamster IgG2, κ
ReactivityMouse
ConjugationABflo® 500. Ex:410nm. Em:501nm.
ApplicationFC
Working DilutionsFC:≤0.25 µg per million cells in 100 µl volume
ImmunogenThis information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at 4℃. Avoid freeze.; Buffer: PBS with 0.09% Sodium azide and BSA, pH7.2.
Regulatory StatusResearch Use Only

Scientific Background

Predicted to enable signaling receptor activity. Involved in negative regulation of immune response. Acts upstream of or within negative regulation of B cell apoptotic process; negative regulation of tolerance induction; and positive regulation of T cell apoptotic process. Located in external side of plasma membrane. Is expressed in retina. Used to study dilated cardiomyopathy and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in autoimmune disease (multiple); hepatitis B; hepatitis C; hepatocellular carcinoma; and lupus nephritis. Orthologous to human PDCD1 (programmed cell death 1).

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