ABflo® 594 Rabbit anti-Human BTN3A1/2/3 mAb,ABclonal,A24823

Reactivity

Human

Application

FC

Conjugate

ABflo® 594. Ex:588nm. Em:604nm.

Platform ID

BAB807791598

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NameABflo® 594 Rabbit anti-Human BTN3A1/2/3 mAb
Cat. No.A24823
RRID#N/A
IsotypeIgG
ReactivityHuman
ConjugationABflo® 594. Ex:588nm. Em:604nm.
ApplicationFC
Working DilutionsFC:5 μl per 10^6 cells in 100 μl volume
Clone NumberARC63604
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at 2-8℃. Avoid freeze.; Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).

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