ABflo® 610 Rabbit anti-Human NAT10 mAb,ABclonal,A28330

Reactivity

Human

Application

FC (intra)

Conjugate

ABflo® 610. Ex:421nm. Em:612nm.

Platform ID

BAB180580160

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NameABflo® 610 Rabbit anti-Human NAT10 mAb
Cat. No.A28330
RRID#N/A
IsotypeIgG
ReactivityHuman
ConjugationABflo® 610. Ex:421nm. Em:612nm.
ApplicationFC (intra)
Working DilutionsFC (intra):5 μl per 10^6 cells in 100 μl volume
Clone NumberARC2468
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at 2-8℃. Avoid freeze.; Buffer: PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

N-acetyltransferase 10 (NAT10) is a member of the Gcn5-related N-acetyltransferase (GNAT) family and it plays a crucial role in various cellular processes, such as regulation of cell mitosis, post-DNA damage response, autophagy and apoptosis regulation, ribosome biogenesis, RNA modification, and other related pathways through its intrinsic protein acetyltransferase and RNA acetyltransferase activities. Moreover, NAT10 is closely associated with the pathogenesis of tumors, Hutchinson-Gilford progeria syndrome (HGPS), systemic lupus erythematosus, pulmonary fibrosis, depression and host–pathogen interactions.

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