ACCN1 antibody,Genetex,GTX54802

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB ICC/IF IP IHC

Conjugate

Unconjugated

Platform ID

BAB694091258

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameACCN1 antibody
Cat. No.GTX54802
Gene ID (Entrez)40
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF IP IHC
ClonalityPolyclonal
Concentration0.3 mg/ml (Please refer to the vial label for the specific concentration.)
TargetASIC2
ImmunogenPeptide DLKESPSEGSLQPSSIQC, corresponding to amino acid residues 2-18 (Intracellular, N-terminus) of human ASIC2a (Accession Q16515).
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
FormulationPBS, 1% BSA, 5% Sucrose,0.025% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Feb 2012]

Synonyms

acid sensing ion channel subunit 2 , ACCN , ACCN1 , ASIC2a , BNC1 , BNaC1 , MDEG , hBNaC1

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