ACSL1 (D2H5) Rabbit Monoclonal Antibody#9189,Cell Signaling Technology (CST),9189

ACSL1 (D2H5) Rabbit Monoclonal Antibody recognizes endogenous levels of total ACSL1 protein.

Host

Rabbit

Reactivity

Human, Mouse, Rat, Monkey

Application

Western Blotting: 1:1000 Immunoprecipitation: 1:50

Platform ID

BAB524471335

Cell Signaling Technology (CST)

Headquarters

3 Trask Lane Danvers, MA 01923

Cell Signaling Technology (CST)

Contact

Tel: 877-616-2355,978-867-2388
Fax: 877-616-2355

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameACSL1 (D2H5) Rabbit Monoclonal Antibody#9189
Cat. No.9189
Accession NumberP33121
Gene ID (Entrez)33121, 2180
HostRabbit
SensitivityEndogenous
ReactivityHuman, Mouse, Rat, Monkey
ApplicationWestern Blotting: 1:1000 Immunoprecipitation: 1:50
Molecular Weight78
ImmunogenIgG
FormulationSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
StorageSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Regulatory StatusResearch Use Only

Scientific Background

Mammalian long-chain acyl-CoA synthetase (ACSL) catalyzes the ligation of the fatty acid to CoA to form fatty acyl-CoA in a two-step reaction (1). Five isoforms of ACSL have been identified (1). These isoforms have different substrate preferences and subcellular localizations (1). Overexpression of ACSL1 results in changes to fatty acid metabolism in rat primary hepatocytes (2).Mashek, D.G. et al. (2004)J Lipid Res45, 1958-61.Li, L.O. et al. (2006)J Biol Chem281, 37246-55.Alternate NamesACS1; ACSL1; Acyl-CoA synthetase 1; acyl-CoA synthetase long chain family member 1; acyl-CoA synthetase long-chain family member 1; Arachidonate--CoA ligase; FACL1; FACL2; fatty-acid-Coenzyme A ligase, long-chain 1; fatty-acid-Coenzyme A ligase, long-chain 2; LACS; LACS 1; LACS 2; LACS1; LACS2; lignoceroyl-CoA synthase; Long-chain acyl-CoA synthetase 1; Long-chain acyl-CoA synthetase 2; Long-chain fatty acid-CoA ligase 2; long-chain fatty-acid-coenzyme A ligase 1; Long-chain-fatty-acid--CoA ligase 1; Palmitoyl-CoA ligase 1; Palmitoyl-CoA ligase 2; paltimoyl-CoA ligase 1; Phytanate--CoA ligase

Synonyms

ACS1; ACSL1; Acyl-CoA synthetase 1; acyl-CoA synthetase long chain family member 1; acyl-CoA synthetase long-chain family member 1; Arachidonate--CoA ligase; FACL1; FACL2; fatty-acid-Coenzyme A ligase, long-chain 1; fatty-acid-Coenzyme A ligase, long-chain 2; LACS; LACS 1; LACS 2; LACS1; LACS2; lignoceroyl-CoA synthase; Long-chain acyl-CoA synthetase 1; Long-chain acyl-CoA synthetase 2; Long-chain fatty acid-CoA ligase 2; long-chain fatty-acid-coenzyme A ligase 1; Long-chain-fatty-acid--CoA ligase 1; Palmitoyl-CoA ligase 1; Palmitoyl-CoA ligase 2; paltimoyl-CoA ligase 1; Phytanate--CoA ligase

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