ADAM22 antibody [GT85],Genetex,GTX641940

Host

Mouse

Reactivity

Mouse

Application

WB

Conjugate

Unconjugated

Platform ID

BAB656398095

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameADAM22 antibody [GT85]
Cat. No.GTX641940
Gene ID (Entrez)53616
HostMouse
IsotypeIgG2b
ReactivityMouse
ConjugationUnconjugated
ApplicationWB
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetADAM22
ImmunogenThe immunogen used to generate this antibody corresponds to human ADAM22.
PurityAffinity purified by Protein A.
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.[provided by RefSeq, Dec 2010]

Synonyms

ADAM metallopeptidase domain 22 , ADAM 22 , EIEE61 , MDC2

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