ADP ribosylation factor 6 (Arf6) Rabbit Polyclonal Antibody,Medimabs,MM-0126

Host

Rabbit

Reactivity

Human

Application

IHC, WB

Platform ID

BAB211852498

Medimabs

Headquarters

141 avenue du President-Kennedy 6th floor, Suite SB-6570 Montreal (Quebec) Canada, H2X 1Y4

Medimabs

Contact

Tel: 1 (514) 940-MABS (6227)
Fax: 1 (514) 733-1212

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameADP ribosylation factor 6 (Arf6) Rabbit Polyclonal Antibody
Cat. No.MM-0126
HostRabbit
SensitivityThe antibody recognizes the human human ADP ribosylation factor 6 (Arf6) protein.
ReactivityHuman
ApplicationIHC, WB
Working DilutionsIf reconstituted with deionized water in 100 µL: WB: 1:2000; IHC: 1:100-1:250. Optimal dilution has to be determined by the user.
ClonalityPolyclonal
Clone Number---
TargetADP ribosylation factor 6 (Arf6)
Appearance/FormLyophilized serum
StorageLyophilized antibodies can be kept at 4ºC for up to 3 months and should be kept at -20ºC for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80ºC) or kept at 4ºC for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.
Regulatory StatusResearch Use Only

Scientific Background

The ARF subfamily comprises a group of proteins that are members of the Ras superfamily of small guanosine triphosphatases (small GTPases). Six ARFs have been identified by related gene products from different species. These 6 members can be divided into three classes on the basis of their size and amino acid sequence homology. ARF6 is the only member of the Class III. ARF6 has a variety of cellular functions that are frequently involved in trafficking of biological membranes and transmembrane protein cargo and has specifically been implicated in endocytosis of plasma membrane proteins and plasma membrane protein recycling.

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