ADSL antibody [2D10],Genetex,GTX84956

Host

Mouse

Reactivity

Human, Rat, Dog, Monkey

Application

WB IHC-P FCM

Conjugate

Unconjugated

Platform ID

BAB572515849

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameADSL antibody [2D10]
Cat. No.GTX84956
Gene ID (Entrez)158
HostMouse
IsotypeIgG1
ReactivityHuman, Rat, Dog, Monkey
ConjugationUnconjugated
ApplicationWB IHC-P FCM
ClonalityMonoclonal
Concentration0.55 mg/ml (Please refer to the vial label for the specific concentration.)
TargetADSL
ImmunogenFull length human recombinant protein of human ADSL (NP_000017) produced in HEK293T cell.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS, 1% BSA, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Synonyms

adenylosuccinate lyase , AMPS , ASASE , ASL

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