AFAP Polyclonal Antibody,Bioss,bs-9790R

Host

Rabbit

Reactivity

Human

Application

WB, IHC-P, IF(IHC-P)

Conjugate

Unconjugated

Platform ID

BAB190151655

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameAFAP Polyclonal Antibody
Cat. No.bs-9790R
Accession NumberQ8N556
Gene ID (Entrez)60312
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IHC-P, IF(IHC-P)
Working DilutionsWB:1:300-5000 | IHC-P:1:200-400 | IF(IHC-P):1:50-200
ClonalityPolyclonal
Concentration1ug/ul
PurityPurified by Protein A.
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Can cross-link actin filaments into both network and bundle structures (By similarity). May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.

Synonyms

AFAP; AFAP110; AFAP-110; Actin filament-associated protein 1; 110 kDa actin filament-associated protein; AFAP1

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