AHR Rabbit pAb- ABclonal,ABclonal,A28506

Reactivity

Mouse

Application

WB, ELISA

Conjugate

Unconjugated

Platform ID

BAB738413651

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NameAHR Rabbit pAb- ABclonal
Cat. No.A28506
RRID#N/A
IsotypeIgG
ReactivityMouse
ConjugationUnconjugated
ApplicationWB, ELISA
Working DilutionsWB:1:1000 - 1:3000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.For high-ratio antibody dilutions (≥1:10000)a sequential dilution method is strongly recommended to ensure measurement accuracy.
Molecular Weight100 kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. Two transcript variants encoding different isoforms have been found for this gene.

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