AIF1/IBA1 Rabbit mAb,ABclonal,A19776

Reactivity

Human, Mouse, Rat, Cynomolgus monkey

Application

WB, IF-F, IF-P, IHC-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB844596452

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameAIF1/IBA1 Rabbit mAb
Cat. No.A19776
Accession NumberO70200(mouse),P55008(Human)
Gene ID (Entrez)11629
RRIDAB_3711469
IsotypeIgG
ReactivityHuman, Mouse, Rat, Cynomolgus monkey
ConjugationUnconjugated
ApplicationWB, IF-F, IF-P, IHC-P, ELISA
Working DilutionsWB:1:1000 - 1:4000 | IF-F:1:200 - 1:2000 | IF-P:1:200 - 1:2000 | IHC-P:1:10000 - 1:40000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC2301
Molecular Weight17kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

Enables actin filament binding activity and calcium ion binding activity. Involved in several processes, including Rac protein signal transduction; actin filament organization; and ruffle assembly. Acts upstream of or within actin filament bundle assembly. Located in several cellular components, including actin filament; phagocytic cup; and ruffle membrane. Is expressed in adrenal cortex; central nervous system; embryo mesenchyme; and retina. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human AIF1 (allograft inflammatory factor 1).

Synonyms

G1; Iba1; AIF-1; D17H6S50E; AIF1/IBA1

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