AKT antibody,Genetex,GTX128415

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]

AKT antibody , MGC99656 antibody , PKB antibody , PKB-ALPHA antibody , PRKBA antibody , RAC antibody , RAC-ALPHA antibody , AKT1 antibody , protein kinase B alpha antibody , rac protein kinase alpha antibody , RAC-alpha serine/threonine-protein kinase antibody , proto-oncogene c-Akt antibody , RAC-PK-alpha antibody , PKB alpha antibody , v-akt murine thymoma viral oncogene homolog 1 antibody , PKBB antibody , PKBBETA antibody , PRKBB antibody , RAC-BETA antibody , AKT2 antibody , protein kinase B beta antibody , murine thymoma viral (v-akt) homolog-2 antibody , protein kinase Akt-2 antibody , RAC-PK-beta antibody , PKB beta antibody , rac protein kinase beta antibody , RAC-beta serine/threonine-protein kinase antibody , v-akt murine thymoma viral oncogene homolog 2 antibody , DKFZp434N0250 antibody , PKB-GAMMA antibody , PKBG antibody , PRKBG antibody , RAC-PK-gamma antibody , RAC-gamma antibody , STK-2 antibody , AKT3 antibody , PKB gamma antibody , RAC-gamma serine/threonine-protein kinase antibody , RAC-gamma serine/threonine protein kinase antibody , v-akt murine thymoma viral oncogene homolog 3 (protein kinase B , gamma) antibody