AKT2 Polyclonal Antibody, HRP Conjugated,Bioss,bs-2056R-HRP

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, ELISA, IHC-P, IHC-F

Conjugate

HRP

Platform ID

BAB487765054

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameAKT2 Polyclonal Antibody, HRP Conjugated
Cat. No.bs-2056R-HRP
Gene ID (Entrez)208
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationHRP
ApplicationWB, ELISA, IHC-P, IHC-F
Working DilutionsWB:1:300-5000 | ELISA:1:500-1000 | IHC-P:1:200-400 | IHC-F:1:100-500
ClonalityPolyclonal
Concentration1ug/ul
PurityPurified by Protein A.
FormulationAqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageStore at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Scientific Background

IGF-1 leads to the activation of AKT3, which may play a role in regulating cell survival. Capable of phosphorylating several known proteins. Truncated isoform 2/PKB gamma 1 without the second serine phosphorylation site could still be stimulated but to a lesser extent. [subcellular location] Cytoplasmic and membrane-associated after cell stimulation leading to its translocation. In adult tissues, it is highly expressed in brain, lung and kidney, but weakly in heart, testis and liver. In fetal tissues, it is highly expressed in heart, liver and brain and not at all in kidney. Belongs to the Ser/Thr protein kinase family. RAC subfamily.

Synonyms

C AKT; MGC9965; Oncogene AKT1; PKB; PRKBA; Protein Kinase B Alpha; RAC Alpha; RAC; RAC PK Alpha; RAC Serine/Threonine Protein Kinase; vAKT Murine Thymoma Viral Oncogene Homolog 1.

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