ALKBH3 antibody,Genetex,GTX131151

Host

Rabbit

Reactivity

Rat

Application

WB

Conjugate

Unconjugated

Platform ID

BAB530558527

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameALKBH3 antibody
Cat. No.GTX131151
Gene ID (Entrez)221120
HostRabbit
IsotypeIgG
ReactivityRat
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
Concentration2.06 mg/ml (Please refer to the vial label for the specific concentration.)
TargetALKBH3
ImmunogenRecombinant protein encompassing a sequence within the center region of human ALKBH3. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 20% Glycerol,0.025% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM]

Synonyms

alkB homolog 3, alpha-ketoglutaratedependent dioxygenase , ABH3 , DEPC-1 , DEPC1 , PCA1 , hABH3

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