AMPK alpha 1 (phospho Thr174) antibody,Genetex,GTX79143

Host

Rabbit

Reactivity

Human

Application

IHC-P

Conjugate

Unconjugated

Platform ID

BAB056873361

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameAMPK alpha 1 (phospho Thr174) antibody
Cat. No.GTX79143
Gene ID (Entrez)5562
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationIHC-P
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetPRKAA1
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human AMPK1 around the phosphorylation site of threonine 174 (L-R-Tp-S-C).
PurityPurified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.From serum
Appearance/FormLiquid
FormulationPBS, 150mM NaCl, 0.5% BSA, 50% glycerol (Please contact us for BSA-free format),0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Synonyms

AMPK,AMPKa1,PRKAA1,protein kinase AMPactivated catalytic subunit alpha 1,AMPK alpha 1,protein kinase AMP-activated catalytic subunit alpha 1

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