APAF1 Recombinant Antibody, AbBy Fluor-680 Conjugated,Bioss,bsm-61152r-bf680-100ul

Host

Rabbit

Reactivity

Human, Mouse

Application

WB, IF(IHC-P), IF(ICC)

Conjugate

AbBy Fluor-680

Platform ID

BAB798760762

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Product Specifications
Scientific Background
Synonyms

Specifications

NameAPAF1 Recombinant Antibody, AbBy Fluor-680 Conjugated
Cat. No.bsm-61152r-bf680-100ul
Accession NumberO14727
Gene ID (Entrez)317
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ConjugationAbBy Fluor-680
ApplicationWB, IF(IHC-P), IF(ICC)
Working DilutionsWB:1:500-2000 | IF(IHC-P):IFIHC-P1:100-500 | IF(ICC):IFICC1:50-200
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
FormulationAqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageStore at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Scientific Background

Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.

Synonyms

APAF; APAF-1; APAF1; apoptotic peptidase activating factor 1; apoptotic protease activating factor 1; Apoptotic protease-activating factor 1; CED4; DKFZp781B1145; KIAA0413.

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