APC Anti-CD23 antibody [2G8],Abcam,AB25457

Host

Rat

Reactivity

Mouse

Application

Flow Cyt

Conjugate

APC

Platform ID

BAB393389227

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAPC Anti-CD23 antibody [2G8]
Cat. No.AB25457
HostRat
IsotypeIgG2a
ReactivityMouse
ConjugationAPC
ApplicationFlow Cyt
ClonalityMonoclonal
Clone Number2G8
Concentration0.1 mg/mL Batch dependent concentration
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.09% Sodium azide Constituents: PBS, 16% Sucrose
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells (PubMed : 2167225). On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway (PubMed : 7544003). See full target information FCER2

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