APC Anti-CD40 antibody [1C10],Abcam,AB25567
This agonistic antibody closely resembles the gp39/CD40 ligand in it's ability to stimulate the proliferation of small, resting B lymphocytes in the absence of other cofactors. This antibody has been shown to be useful in studies of the 'in vitro' induction of proliferation of mature B lymphocytes.
Host
Rat
Reactivity
Mouse
Application
Flow Cyt
Conjugate
APC
Platform ID
BAB143664095
Abcam
Contact
Tel: +44 (0)1223 696000
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Product Specifications
Scientific Background
Specifications
NameAPC Anti-CD40 antibody [1C10]
Cat. No.AB25567
HostRat
IsotypeIgG2a
ReactivityMouse
ConjugationAPC
ApplicationFlow Cyt
ClonalityMonoclonal
Clone Number1C10
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human CD40. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.09% Sodium azide Constituents: PBS, 16% Sucrose
Storage+4°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Receptor for TNFSF5/CD40LG (PubMed : 31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity). See full target information CD40
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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