APC Anti-IL-2 Receptor alpha antibody [PC61.5],Abcam,AB210330

This antibody is used as a marker for T cells, B cells and dendritic cell subsets. Expression of CD25, CD4 and the transcription factor Foxp3 is regarded as a phenotypic signature for Treg cells. As such, this antibody is widely used to distinguish Treg cells from naïve or conventional T cells which are CD25-.

Host

Rat

Reactivity

Mouse

Application

Flow Cyt

Conjugate

APC

Platform ID

BAB146562703

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAPC Anti-IL-2 Receptor alpha antibody [PC61.5]
Cat. No.AB210330
HostRat
IsotypeIgG1
ReactivityMouse
ConjugationAPC
ApplicationFlow Cyt
ClonalityMonoclonal
Clone NumberPC61.5
Concentration0.2 mg/mL Batch dependent concentration
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.09% Sodium azide Constituents: 0.87% Sodium chloride, 0.12% Sodium dihydrogen phosphate, 0.1% Gelatin
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. See full target information Il2ra

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