APC/Cy7® Anti-RP105 antibody [G28-8],Abcam,AB253257

This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5, 268, 486 and related patents. Cy® and CyDye® are trademarks of Cytiva.

Host

Mouse

Reactivity

Human

Application

Flow Cyt

Conjugate

APC/Cy7®

Platform ID

BAB269925989

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAPC/Cy7® Anti-RP105 antibody [G28-8]
Cat. No.AB253257
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationAPC/Cy7®
ApplicationFlow Cyt
ClonalityMonoclonal
Clone NumberG28-8
ImmunogenCell preparation containing CD180 protein. The exact immunogen used to generate this antibody is proprietary information.
PuritySize-exclusion chromatography
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.0975% Sodium azide Constituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Pattern recognition receptor predominantly expressed on B-cells, dendritic cells, and certain monocytes/macrophages, structurally resembling Toll-like receptors (TLRs) that plays a role in modulating immune responses (PubMed : 15852007). While ressembling a TLR, lacks the intracellular TIR (Toll/IL-1R) signaling domain and thus does not directly transduce signals. Instead, modulates immune responses, often in conjunction with other TLRs. For example, in cooperation with MD-1/LY86, interacts directly with the TLR4 signaling complex, inhibiting its ability to bind microbial ligand (PubMed : 15852007). See full target information CD180

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.