APC/Cyanine7 anti-human CD134 OX40 Antibody anti-CD134 - Ber-ACT35 (ACT35),BioLegend,350021

Additional reported applications (for the relevant formats) include: Western blotting1, immunoprecipitation1, immunohistochemical staining2,3of paraffin embedded7and frozen tissue sections, ELISA4, and functional assay5. The LEAF™ or Ultra-LEAF™ purified antibody is recommended for functional assays (contact ourcustom solutions team).

Host

Mouse

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB021767691

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameAPC/Cyanine7 anti-human CD134 OX40 Antibody anti-CD134 - Ber-ACT35 (ACT35)
Cat. No.350021
HostMouse
RRIDAB_2571941 (BioLegend Cat. No. 350021)AB_2571942 (BioLegend Cat. No. 350022)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberBer-ACT35 (ACT35)
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD134
ImmunogenHTLV 1-transformed HUT 102 cells
PurityThe antibody was purified by affinity chromatography and conjugated with APC/Cyanine7 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD134, also known as OX40 and TNFRSF4, is a 50 kD type I transmembrane glycoprotein. It is a member of the TNF receptor family. OX40 is expressed on activated T lymphocytes including Th1, Th2, Th17, and Treg cells. The interaction of OX40 with OX40L results in B cell proliferation and antibody secretion, regulation of primary T cell expansion, and T cell survival. OX40 influences the size of the T cell memory pool and regulation of CD4+T cell tolerance.

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