APC/Cyanine7 anti-human CD146 antibody, CD146, P1H12,BioLegend,361042
Additional reported applications (for the relevant formats of this clone) include: Western blotting3and IHC1,5.Clone P1H12 cross-reacts to Dog2, 5.
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB889197562
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAPC/Cyanine7 anti-human CD146 antibody, CD146, P1H12
Cat. No.361042
HostMouse
RRIDAB_2894492 (BioLegend Cat. No. 361041)AB_2894492 (BioLegend Cat. No. 361042)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberP1H12
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD146
ImmunogenCultured human umbilical cells
PurityThe antibody was purified by affinity chromatography and conjugated with APC/Cyanine7 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD146 is a 118 kD integral transmembrane glycoprotein that is also known as MUC18, S-Endo, MCAM, and Mel-CAM (melanoma cell adhesion molecule). It belongs to the immunoglobulin superfamily. CD146 is expressed on melanoma cells, epithelial cells, endothelial cells, fibroblasts, activated T cells, multipotent mesenchymal stromal cells, and activated keratinocytes. CD146 mediates heterophilic cell adhesion and regulates monocyte transendothelial migration. The ligand of CD146 remains to be identified.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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