APC/Cyanine7 anti-human CD27,BioLegend,384911
Clone S20020G is able to completely block the binding of clones M-T271 and O323 on target cells. Clone S20020G does not block binding of clone S20020H on target cells.
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB510900381
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameAPC/Cyanine7 anti-human CD27
Cat. No.384911
HostMouse
RRIDAB_3675096 (BioLegend Cat. No. 384911)AB_3675096 (BioLegend Cat. No. 384912)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberS20020G
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD27
ImmunogenHu CD27 transfected cells
PurityThe antibody was purified by affinity chromatography and conjugated with APC/Cyanine7 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD27, also known as S152 and T14, is a 50-55 kD type I membrane protein. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation, and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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