APC/Cyanine7 anti-human CD294 CRTH2 Antibody anti-CD294 - BM16,BioLegend,350114
This product is sold under license agreement with BML, Inc for research use only.
Host
Rat
Reactivity
Human
Application
FC -Quality tested
Platform ID
BAB897704741
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Product Specifications
Scientific Background
Specifications
NameAPC/Cyanine7 anti-human CD294 CRTH2 Antibody anti-CD294 - BM16
Cat. No.350114
HostRat
RRIDAB_2562464 (BioLegend Cat. No. 350113)AB_2562465 (BioLegend Cat. No. 350114)
IsotypeRat IgG2a, κ
ReactivityHuman
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberBM16
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD294
ImmunogenRat cell line TART/B19-12.10 transfected with human CRTH2
PurityThe antibody was purified by affinity chromatography and conjugated with APC/Cyanine7 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD294, also known as CRTH2, is a seven-transmembrane protein coupled with heterotrimeric G proteins. CRTH2 is the prostaglandin D2 receptor and is expressed by Th2 cells, eosinophils, and basophils. CD294 prevents the apoptosis of Th2 cells and mediates the chemotaxis of CRTH2 expressing cells to the sites of allergic inflammation, such as the asthmatic lung.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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