APC/Cyanine7 anti-mouse CD184 (CXCR4) Antibody, CD184, L276F12,BioLegend,146524
Additional reported applications (for the relevant formats) include:in vivoblocking1
Host
Rat
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB808813636
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameAPC/Cyanine7 anti-mouse CD184 (CXCR4) Antibody, CD184, L276F12
Cat. No.146524
HostRat
RRIDAB_2904292 (BioLegend Cat. No. 146523)AB_2904292 (BioLegend Cat. No. 146524)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberL276F12
Concentration0.2 mg/mL
TargetCD184
ImmunogenMouse CXCR4-transfected cells
PurityThe antibody was purified by affinity chromatography and conjugated with APC/Cyanine7 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD184, also known as CXCR4, is a member of the G protein coupled receptor family that binds CXCL12 (SDF1). CXCR4 and CXCL12 play an important role in immune and inflammatory responses through the regulation of cell migration and growth. CXCR4 plays a crucial role in the pathogenesis of several autoimmune diseases such as atherosclerosis, rheumatoid arthritis, and wound healing. In addition, CXCR4 is the cofactor for fusion and entry of the T cell-tropic form of HIV-1.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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