APC/Fire™ 750 anti-human β2-microglobulin Antibody, β2-microglobulin, A17082E,BioLegend,395807
Based on in-house testing, staining for clone A17082E is not blocked by clone W6/32 (anti-HLA-A,B,C) and is only partially blocked by clone 2M2 also raised against human ß2-microglobulin.
Host
Mouse
Reactivity
Human
Application
FC -Quality tested
Platform ID
BAB737436649
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameAPC/Fire™ 750 anti-human β2-microglobulin Antibody, β2-microglobulin, A17082E
Cat. No.395807
HostMouse
RRIDAB_2810593 (BioLegend Cat. No. 395807)AB_2810594 (BioLegend Cat. No. 395808)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberA17082E
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
Targetbeta2-microglobulin
ImmunogenRecombinant human Beta2-microglobulin
PurityThe antibody was purified by affinity chromatography and conjugated with APC/Fire™ 750 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
β2-microglobulin (β2M) is a 12 kD nonpolymorphic Ig like protein. It is a non-membrane-anchored glycoprotein and is noncovalently associated with 39-44 kD polymorphic heavy chains of MHC class I molecules to form HLA class I antigen complex. In association with HLA class I, β2M is expressed on all leukocytes, platelets, endothelial cells, and epithelial cells. β2M plays an essential role both in governing MHC class I molecules stability and in promoting antigen binding and presenting the antigen to CD3/TCR complex of CD8+T cells.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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