APC/Fire™ 750 anti-human CD288 (TLR8) Antibody, CD288, S16018A,BioLegend,395516
Host
Mouse
Reactivity
Human
Application
ICFC - Quality tested
Platform ID
BAB442222098
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameAPC/Fire™ 750 anti-human CD288 (TLR8) Antibody, CD288, S16018A
Cat. No.395516
HostMouse
RRIDAB_3097530 (BioLegend Cat. No. 395515)AB_3097530 (BioLegend Cat. No. 395516)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationICFC - Quality tested
ClonalityMonoclonal
Clone NumberS16018A
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD288
ImmunogenHuman TLR8-transfected cells
PurityThe antibody was purified by affinity chromatography and conjugated with APC/Fire™ 750 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
Toll-like receptor (TLR) 8, also known as CD288, is a 83 kDa, type 1 transmembrane protein, member of the TLR receptor family. TLR8 is expressed intracellulary in monocytes, macrophages and myeloid dendritic cells, and plays an important role in the innate immune response by binding single-stranded RNA (ssRNA). TLR8 triggers anti-viral reponses promoting the secretion of proinflammatory cytokines such as IL-12 and TNF.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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