APC/Fire™ 750 anti-human HLA-DR Antibody, HLA-DR, LN3,BioLegend,327024

Additional reported applications (for the relevant formats) include: immunohistochemical staining1of frozen sections and formalin-fixed paraffin-embedded sections1, and immunoprecipitation1.

Host

Mouse

Reactivity

Human

Application

FC -Quality tested

Platform ID

BAB182712929

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameAPC/Fire™ 750 anti-human HLA-DR Antibody, HLA-DR, LN3
Cat. No.327024
HostMouse
RRIDAB_2810491 (BioLegend Cat. No. 327023)AB_2810492 (BioLegend Cat. No. 327024)
IsotypeMouse IgG2b, κ
ReactivityHuman
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberLN3
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetHLA-DR
Immunogenhuman PBL
PurityThe antibody was purified by affinity chromatography and conjugated with APC/Fire™ 750 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

The LN3 monoclonal antibody reacts with the HLA-DR antigen, a member of MHC class II molecules. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+T cells.

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