APC/Fire 750 anti-human beta2-microglobulin Antibody anti-beta2-microglobulin - 2M2,BioLegend,316313
Additional reported applications (for the relevant formats) include: Western blotting, and ELISA.
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB275768241
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameAPC/Fire 750 anti-human beta2-microglobulin Antibody anti-beta2-microglobulin - 2M2
Cat. No.316313
HostMouse
RRIDAB_2632825 (BioLegend Cat. No. 316313)AB_2632826 (BioLegend Cat. No. 316314)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number2M2
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
Targetbeta2-microglobulin
ImmunogenPurified human β2-microglobulin
PurityThe antibody was purified by affinity chromatography and conjugated with APC/Fire™ 750 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
β2-microglobulin (β2M) is a 12 kD nonpolymorphic Ig like protein. It is a non-membrane-anchored glycoprotein and is noncovalently associated with 39-44 kD polymorphic heavy chains of MHC class I molecules to form HLA class I antigen complex. In association with HLA class I, β2M is expressed on all leukocytes, platelets, endothelial cells, and epithelial cells. β2M plays an essential role both in governing MHC class I molecules stability and in promoting antigen binding and presenting the antigen to CD3/TCR complex of CD8+T cells.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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