APC/Fire™ 750 anti-human/mouse Granzyme B Recombinant Antibody, Granzyme B, QA18A28,BioLegend,396417
Clone QA18A28 is compatible with Fixation buffer (Cat. No. 420801) and Intracellular Staining Permeabilization Wash Buffer (Cat. No. 421002) in both C57BL/6 splenocytes and human PBMC. QA18A28 is also compatible with True-Nuclear™ Transcription Factor Buffer Set (Cat. No. 424401).
Host
Rat
Reactivity
Human, Mouse
Application
ICFC - Quality tested
Platform ID
BAB375642807
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAPC/Fire™ 750 anti-human/mouse Granzyme B Recombinant Antibody, Granzyme B, QA18A28
Cat. No.396417
HostRat
RRIDAB_2924598 (BioLegend Cat. No. 396417)AB_2924598 (BioLegend Cat. No. 396418)
IsotypeRat IgG1, κ
ReactivityHuman, Mouse
ApplicationICFC - Quality tested
ClonalityRecombinant
Clone NumberQA18A28
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetGranzyme B
PurityThe antibody was purified by affinity chromatography and conjugated with APC/Fire™ 750 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
Granzyme B is a 32 kD serine protease, also known as granzyme-2, serine protease B, CCP1, Asp-ase, and CTLA-1. Granzyme B is abundantly stored in the granules of cytotoxic T lymphocytes and NK cells. Low level of expression has been reported in granulocytes, B cells, and activated dendritic cells. Granzyme B is crucial for rapid induction of cell death and apoptosis through interaction with mannose-6-phosphate receptor.
Category Paths
- Products>Primary Antibodies>Recombinant Antibodies
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