APC/Fire™ 810 anti-human CD289 (TLR9) Antibody, CD289, S16013D,BioLegend,394811

S16013D clone can be used for both surface and intracellular detection of TLR9. ICFC compatible with both theintracellular flow cytometric stainingandTrue-Nuclear™ transcription buffer set. Does not work for WB (tested on Daudi cell line).

Host

Rat

Reactivity

Human

Application

ICFC - Quality tested

Platform ID

BAB066734832

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameAPC/Fire™ 810 anti-human CD289 (TLR9) Antibody, CD289, S16013D
Cat. No.394811
HostRat
RRIDAB_2927844 (BioLegend Cat. No. 394811)AB_2927844 (BioLegend Cat. No. 394812)
IsotypeRat IgG2a, κ
ReactivityHuman
ApplicationICFC - Quality tested
ClonalityMonoclonal
Clone NumberS16013D
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD289
ImmunogenCD289 (TLR9)
PurityThe antibody was purified by affinity chromatography and conjugated with APC/Fire™ 810 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

TLR9 is a member of the toll-like receptor family that aids in recognition of pathogen associated molecular patterns (PAMPs). TLR9 recognizes unmethylated CpG sequences in DNA (ie. intracellular bacteria and DNA viruses). TLR9 signals through the MyD88 pathway leading to inflammatory cytokine production, especially production of type I interferons by pDCs.

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