APC Rabbit anti-Human CD141/Thrombomodulin mAb,ABclonal,A26515

Reactivity

Human

Application

FC

Conjugate

APC. Ex:650nm. Em:660nm.

Platform ID

BAB997734175

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NameAPC Rabbit anti-Human CD141/Thrombomodulin mAb
Cat. No.A26515
RRID#N/A
IsotypeIgG
ReactivityHuman
ConjugationAPC. Ex:650nm. Em:660nm.
ApplicationFC
Working DilutionsFC:5 μl per 10^6 cells in 100 μl volume
Clone NumberARC52599
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at 2-8℃. Avoid freeze.; Buffer: PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.

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