APC Rabbit anti-NHP CD45 mAb,ABclonal,A28472
Reactivity
Cynomolgus, Rhesus
Application
FC
Conjugate
APC. Ex:650nm. Em:660nm.
Platform ID
BAB751207507
ABclonal
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Product Specifications
Scientific Background
Specifications
NameAPC Rabbit anti-NHP CD45 mAb
Cat. No.A28472
RRID#N/A
IsotypeIgG
ReactivityCynomolgus, Rhesus
ConjugationAPC. Ex:650nm. Em:660nm.
ApplicationFC
Working DilutionsFC:5 μl per 10^6 cells in 100 μl volume
Clone NumberARC79398
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at 2-8℃. Avoid freeze.; Buffer: PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3.
Regulatory StatusResearch Use Only
Scientific Background
CD45 is a receptor-type protein tyrosine phosphatase, also known as Ly-5 or the leukocyte common antigen. It functions primarily by regulating the activation of Src family protein tyrosine kinases, such as Lck and Fyn, thereby initiating T cell receptor signaling. Deficiency in CD45 results in dysfunctional T and B lymphocytes, leading to severe combined immunodeficiency. Furthermore, CD45 plays a significant role in the pathogenesis of autoimmune diseases, cancer, and infectious diseases, including fungal infections.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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