APC anti-MEK1 Phospho (Ser298) Antibody, MEK1 Phospho (Ser298), A16117B,BioLegend,610608
Host
Mouse
Reactivity
Human, Mouse
Application
ICFC - Quality tested
Platform ID
BAB173805942
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAPC anti-MEK1 Phospho (Ser298) Antibody, MEK1 Phospho (Ser298), A16117B
Cat. No.610608
HostMouse
RRIDAB_2888737 (BioLegend Cat. No. 610607)AB_2888737 (BioLegend Cat. No. 610608)
IsotypeMouse IgG1, κ
ReactivityHuman, Mouse
ApplicationICFC - Quality tested
ClonalityMonoclonal
Clone NumberA16117B
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetMEK1 Phospho Ser298
ImmunogenHuman MEK1 peptide phosphorylated at Ser298. Complete Freund’s adjuvant.
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
MEK1 and MEK2 (Map/Erk Kinase) are serine/threonine kinases in the MAPK/ERK signaling axis that play a critical role in cellular proliferation, differentiation, and migration. Phosphorylation at MEK1 (Ser298) by PAK1 enhances the ability of upstream Raf kinases to phosphorylate regulatory serines (Ser218 and Ser222) in the activation loop, thereby stimulating kinase activity.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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