APC anti-human C3AR Antibody anti-C3aR - hC3aRZ8,BioLegend,345806
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections2.
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB916795573
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAPC anti-human C3AR Antibody anti-C3aR - hC3aRZ8
Cat. No.345806
HostMouse
RRIDAB_10899735 (BioLegend Cat. No. 345805)AB_10899569 (BioLegend Cat. No. 345806)
IsotypeMouse IgG2b, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberhC3aRZ8
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetC3aR
ImmunogenhC3aR transfected cells
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
C3AR is a single chain protein of 482 aa, with seven membrane-spanning regions and a molecular weight of 54 Kd. C3AR is expressed by neutrophils, eosinophils, mast cells, monocytes, dendritic cells and there are reports of C3AR expression in non-immune cells such as hematopoietic and mesenchymal stem cells, epithelial and endothelial cells. C3AR is coupled to heterotrimeric G proteins and after C3a binding, the signal transduced, results in chemotaxis, granule enzyme release and superoxide anion production.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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