APC anti-human CD143 Angiotensin-converting enzyme Antibody anti-CD143 - 5-369,BioLegend,344206
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB437646824
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAPC anti-human CD143 Angiotensin-converting enzyme Antibody anti-CD143 - 5-369
Cat. No.344206
HostMouse
RRIDAB_11149487 (BioLegend Cat. No. 344206)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number5-369
ConcentrationLot-specific (to obtain lot-specific concentration, please enter the lot number in ourConcentration and Expiration LookuporCertificate of Analysisonline tools.)
TargetCD143
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD143 (ACE, kininase II, peptidyl dipeptidase 1, peptidase P, carboxycathepsin) is a 171 kD, type I, single chain transmembranal metallopeptidase, whose cofactor is zinc. Its main targets are angiotensin I and bradykinin, acting as a blood pressure regulator. CD143 is expressed in endothelial cells; varying amounts of CD143 have been reported in different epithelial cells. The activation of macrophages and histiocytes induces the expression of this molecule.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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