APC anti-human CD210b (IL-10RB) antibody, CD210b, S17009F,BioLegend,396806
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB880290575
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAPC anti-human CD210b (IL-10RB) antibody, CD210b, S17009F
Cat. No.396806
HostMouse
RRIDAB_2892467 (BioLegend Cat. No. 396805)AB_2892467 (BioLegend Cat. No. 396806)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberS17009F
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD210b
ImmunogenHuman IL10RB-transfected cells
PurityThe antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD210b is a Type 1 transmembrane glycoprotein also known as, subunit 2 (IL-10R2) and is an essential chain for the IL-10 receptor complex. The IL-10 receptor complex is made up of alpha (IL10-RA) and beta (IL-10RB) subunits. Coexpression of these subunits has been shown to be required for IL10 induced signal transduction. Binding of dimeric IL-10 to two alpha subunits can cause the recruitment of two beta subunits resulting in the transduction of the intracellular JAK/STAT pathway.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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